PET Tracers
×
By leveraging cutting-edge radiosynthesis technologies, we are able to offer a wide range of tracers on a per-batch basis. Generally, production must be requested at least 2 weeks in advance to allow sufficient time for ordering any needed materials and for coordinating any associated imaging studies, as applicable.
Standard analytical test results are available with all batches (e.g. radiochemical identity and purity). Please contact us if specialized tests (e.g. molar activity) are needed.
Available PET Tracers
The Radiochemistry Center is fully-equipped for production of 18F-labeled tracers. By leveraging cutting-edge technologies for PET tracer production, we are able to offer a wide range of tracers. Generally, production must be requested at least 2 weeks in advance to allow sufficient time for ordering any needed materials and for coordinating any associated imaging studies, if applicable.
PET Probes |
Type |
Biological Application |
18F-FDG |
glucose |
glycolysis (cancer biology, neuroscience, etc) |
18F-NaF |
bone appetite crystals |
bone metabolism; cancer biology (e.g. prostate cancer bone metastasis) |
18F-FLT |
thymidine (nucleoside) |
proliferation; nucleoside metabolism (e.g. cancer biology, immunology) |
18F-FHBG |
nucleoside |
reporter gene imaging |
18F-D-FAC (and analogs) |
deoxycytidine (nucleoside) |
immunology (e.g. adaptive immune response; immunotherapies)
cancer biology (e.g. treatment stratification of nucleoside analog prodrugs) |
18F-L-FMAU (and analogs) |
nucleoside |
reporter gene imaging |
18F-D-FEAU |
nucleoside |
reporter gene imaging (e.g. cell trafficking and cellular function) |
124I-FIAU |
nucleoside |
reporter gene imaging (e.g. cell trafficking and cellular function) |
18F-Fallypride |
D2 receptor ligand |
neuroscience |
18F-FDHT |
testosterone |
cancer biology (prostate cancer) |
18F-AraG |
guanosine (nucleoside) |
immunology; cancer biology |
18F-FDOPA |
amino acid (phenylalanine) |
dopamine synthesis: neuroscience & brain tumors |
18F-FDDNP |
amyloid ligand |
neuroscience: Alzheimer's & other amyloid disorders |
11C-acetate |
acetate |
cancer biology (prostate cancer)
fatty acid synthesis |
13N-ammonia |
ammonia |
blood flow at the capillary level (perfusion) |
11C-L-glutamine |
glutamine |
cancer biology; glutamine metabolism |
18F-clofarabine (18F-CFA) |
deoxycytidine (nucleoside) |
immunology (e.g. adaptive immune response; immunotherapies)
cancer biology (e.g. treatment stratification of nucleoside analog prodrugs) |
18F-flumazenil (18F-FMZ) |
benzodiazepene receptor ligand |
neuroscience |
18F-florbetaben (18F-FBB) |
amyloid ligand |
neuroscience: Alzheimer's & other amyloid disorders |
18F-FPEB |
metabotropic glutamate receptor, type 5 ligand |
neuroscience |
18F-LY2459989 |
kappa opiod receptor (KOR) antagonist |
|
18F-FEPPA |
TSPO ligand |
neuroinflammation, neurodegeneration |
18F-PBR06 |
TSPO ligand |
neuroinflammation, neurodegeneration |
18F-FET |
amino acid |
amino acid transport; tumor imaging |
18F-AMBF3-TATE |
somatostatin analogs |
cancer biology (e.g. neuroendocrine tumors) |
68Ga-DOTATATE* |
somatostatin analogs |
cancer biology (e.g. neuroendocrine tumors) |
11C-choline* |
choline |
cancer biology (e.g. prostate cancer) |
18F-fluorobenzyl triphenylphosphonium (18FBnTP)* |
mitochondrial membrane potential |
cancer; myocardial perfusion |
*Future offer
Protein, Peptide and Nanoparticle Labeling
We can perform random and site-specific 18F labeling of appropriately functionalized peptides, proteins or particles via the following prosthetic groups:
- 18F-SFB
- 18F-FNB
- 18F-fluorobenzaldehyde (18F-FBA)
- 18F-FBEM
- 18F-PEG-3-azide
We can also perform labeling of molecules and nanoparticles conjugated to appropriate chelators with additional isotopes:
Other Tracers
If your imaging requires other PET tracers (not listed above) that have been described in literature, we provide services for bringing new tracers online at UCLA. We have a strong record of adapting literature protocols onto our synthesizer modules. Please contact us for estimates of cost and timeframe.